Lithuanian Journal of Physics article / Lietuvos fizikos žurnalo straipsnis

RELAXATION DYNAMICS OF GUANOSINE 5'-MONOPHOSPHATE WITH Na⁺ AND K⁺ IN AQUEOUS SOLUTIONS INVESTIGATED BY BROADBAND DIELECTRIC SPECTROSCOPY
Ilona Zamaraitė, Andrius Džiaugys, and Jūras Banys
Institute of Applied Electrodynamics and Telecommunications, Faculty of Physics, Vilnius University, Saulėtekio 3, 10257 Vilnius, Lithuania
Email: ilona.zamaraite@ff.vu.lt, ORCID: 0000-0002-8558-5014

Received 14 November 2025; revised 9 December 2025; accepted 29 December 2025

To gain insights into nucleotide–monovalent ions interaction, the dynamics of counterions (sodium and potassium) with guanosine 5'-monophosphate (5'-GMP) were studied in an aqueous solution via broadband dielectric spectroscopy measurements. Complex reflection coefficients of aqueous Na-GMP and K-GMP solutions are measured in the frequency domain at room temperature. Complex specific resistance spectra are analyzed at various mononucleotide concentrations. One dispersion region located at 100 MHz was observed. It is interpreted as being caused by DNA counterion fluctuations. It largely depends on the GMP concentration in the solution.
Keywords: dielectric spectroscopy, Na⁺ and K⁺ counterions, relaxation dynamics, biological matter, polyelectrolytes

GUANOZINO 5'-MONOFOSFATO RELAKSACIJOS DINAMIKA NATRIO IR KALIO JONŲ TIRPALUOSE, TIRTA PLAČIAJUOSTE DIELEKTRINE SPEKTROSKOPIJA
Ilona Zamaraitė, Andrius Džiaugys, Jūras Banys

Vilniaus universiteto Fizikos fakulteto Taikomosios elektrodinamikos ir telekomunikacijų institutas, Vilnius, Lietuva

Siekiant geriau suprasti nukleotidų ir monovalentinių jonų sąveiką, šiame darbe tirta guanozino 5'-monofosfato (5'-GMP) dinamika natrio ir kalio vandeniniuose tirpaluose, taikant plačiajuostę dielektrinę spektroskopiją. Gauti kompleksinės specifinės varžos spektrai plačiame dažnių diapazone (nuo 50 MHz iki 40 GHz) skirtingos GMP koncentracijos vandeniniams tirpalams. Dispersijos sritis ties ~100 MHz siejama su priešingo krūvio jonų bei prie mononukleotido paviršiaus sujungto vandens dinamika. Dielektrinės relaksacijos parametrai priklauso nuo GMP koncentracijos ir tirpale esančio monovalentinio jono tipo.

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